A few questions:
- What kind of install for Mailspring are you using (a Deb package, Snap, etc.)?
- Can you start Mailspring from a command line and see what error messages are showing?
If you haven’t already, please see this thread in case it is helpful:
https://community.getmailspring.com/t/password-management-error-after-the-latest-upgrade/7298/14